| The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening. | |
| | |
MedLine Citation:
|
PMID: 2240103 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Universal urine testing for cocaine, amphetamines, and opiates was performed on 1643 women admitted to an obstetric service for a 1-year period with 20.5% having positive results. There were 299 patients with positive toxicology results matched for race and discharge date with patients having negative toxicology and drug history. Significant differences in age, prior obstetric history, prenatal care, alcohol history, and smoking were noted between groups. There was a significant decrease in birth weight, head circumference, length, and gestational age for the drug-positive group, which was most marked in cocaine and multiple drug users. These differences persisted after we controlled for smoking, prenatal care, and prior preterm births. Differences in birth weight and head circumference remained after we controlled for gestational age. Rates of congenital anomalies and abruptio placental were similar between groups. Perinatal substance abuse is independently associated with growth retardation and prematurity. Multiple risk factors are frequently present, necessitating a comprehensive approach to prenatal care. |
| | |
Authors:
|
K M Gillogley; A T Evans; R L Hansen; S J Samuels; K K Batra |
Related Documents
:
|
23189153 - Status of systemic oxidative stresses in patients with primary open-angle glaucoma and ... 23559463 - Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse transcriptase ... 20952863 - A study of palmar dermatoglyphics and palmar freckles. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 163 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1990 Nov |
Date Detail:
|
Created Date: 1990-12-14 Completed Date: 1990-12-14 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1535-42 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, University of California, Davis. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amphetamine* Analysis of Variance Birth Weight / drug effects Body Height / drug effects Chi-Square Distribution Cocaine* Female Gestational Age Humans Infant, Newborn Labor, Obstetric Narcotics* Pregnancy Pregnancy Complications* / diagnosis Pregnancy Outcome* Prenatal Care Regression Analysis Substance Abuse Detection Substance-Related Disorders / complications*, diagnosis |
| Chemical | |
Reg. No./Substance:
|
0/Narcotics; 300-62-9/Amphetamine; 50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nature of gonadotropin-releasing hormone self-priming of luteinizing hormone secretion during the no...
Next Document: Inhibition of aromatase activity by 8-bromo-cyclic adenosine monophosphate in cultured first-trimest...