Document Detail

The peak time difference of time-density curve in intravenous digital subtraction angiography correlates to an asymmetric cerebral blood flow as determined by positron emission tomography.
MedLine Citation:
PMID:  21284774     Owner:  NLM     Status:  In-Data-Review    
A time-density curve study in contrast media transit is theoretically possible to evaluate an asymmetric cerebral perfusion. In this study, we confirmed the correlation between the peak time difference in a regional time-density curve and the asymmetry of cerebral blood flow using positron emission tomography (PET). Five patients with a unilateral occlusion of the carotid or middle cerebral artery underwent intravenous digital subtraction angiography and PET on two successive days. We placed four pairs of regions of interest as appropriate in each study, and obtained the peak time of a regional time-density curve, regional cerebral vascular blood flow (rCVBF) and regional cerebral blood flow (rCBF). We obtained a significant linear correlation between the right-to-left difference of peak time and the difference of 1/rCVBF (r = 0.85, p < 0.001). The peak time difference also showed good correlation to the absolute difference of rCBF (r = -0.84, p < 0.001). A time-density curve study can detect the asymmetry of rCBF, and may be used to evaluate unilateral ischemic damages.
T Imamura; H Nagasawa; M Itoh; K Tsuburaya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of neurology : the official journal of the European Federation of Neurological Societies     Volume:  3     ISSN:  1351-5101     ISO Abbreviation:  Eur. J. Neurol.     Publication Date:  1996 May 
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9506311     Medline TA:  Eur J Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  -    
Copyright Information:
1996 Lippincott Williams & Wilkins.
Department of Neurology, Tohoku University School of Medicine, Sendai, JapanDivision of Nuclear Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, JapanDepartment of Neurology, Tohoku Kohseinenkin Hospital, Sendai, Japan.
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