| The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery. | |
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MedLine Citation:
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PMID: 20830348 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Liposomal nucleic acid delivery is a preferred option for therapeutic settings. The cellular pattern recognition molecule DMBT1, secreted at high levels in various diseases, and synthetic mimics efficiently inhibit liposomal nucleic acid delivery to human cells. These findings may have relevance for therapeutic nucleic acid delivery strategies. |
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Authors:
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Pernille Lund Hansen; Stephanie Blaich; Caroline End; Steffen Schmidt; Jesper B Moeller; Uffe Holmskov; Jan Mollenhauer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-07 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: 47 ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 188-90 Citation Subset: IM |
Affiliation:
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Lundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, 5000 Odense C, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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