Document Detail


A patient with undifferentiated carcinoma of gallbladder presenting with hemobilia.
MedLine Citation:
PMID:  10632545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemobilia is relatively rare among hemorrhages in the digestive tract, and hemobilia caused by tumors of the biliary tract is particularly rare. We treated a 74-year-old-man with undifferentiated carcinoma of the gallbladder presenting with hemobilia. During hospitalization for neurogenic bladder at the Department of Urology, he showed progressive anemia. Since hemorrhage in the digestive tract was suspected, endoscopy of the upper gastrointestinal tract was performed, and bleeding from the papilla of Vater was observed. On ultrasound examination, findings were indicative of cholecystic cancer, and hemorrhage from the cystic duct was found on percutaneous transhepatic cholangioscopy. On perioral cholecystoscopy, however, masses of coagulated blood were found only in the gallbladder. Abnormalities such as dense staining of tumors or extravasation were not found on angiography. The patient died of hepatic failure due to rapid invasion of the liver by the tumor, associated with biliary infection and disseminated intravascular coagulation. At autopsy, a nodal tumor was found in the gallbladder, and the cavity of the gallbladder was filled with coagulated masses of blood. Direct invasion of the tumor to the liver, diaphragm, and transverse colon was found. The histopathological diagnosis was undifferentiated carcinoma (pleomorphic large-cell type).
Authors:
H Kubota; M Kageoka; H Iwasaki; K Sugimoto; R Higuchi; S Honda; F Watanabe; K Koda; H Hanai; E Kaneko
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of gastroenterology     Volume:  35     ISSN:  0944-1174     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2000  
Date Detail:
Created Date:  2000-01-27     Completed Date:  2000-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  63-8     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Fujieda Municipal General Hospital, Surugadai, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Carcinoma / complications*,  pathology
Gallbladder / pathology
Gallbladder Neoplasms / complications*,  pathology
Hemobilia / etiology*
Humans
Male
Neoplasm Invasiveness

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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