| A patient with tracheoesophageal fistula and esophageal cancer after radiotherapy. | |
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MedLine Citation:
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PMID: 21063396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A 63-year-old woman presented with dysphagia owing to proximal esophageal stenosis 27 years after she received radiation therapy for Hodgkin disease. She had previously experienced various other complications of this treatment, including myelopathy, hypothyroidism, and cardiomyopathy. INVESTIGATIONS: Medical history and physical examination, pathology and immunohistochemistry, bronchoscopy, esophagogastroscopy, chest and abdominal PET-CT scan, examination of the thorax during open right thoracotomy. DIAGNOSIS: Large tracheoesophageal fistula and poorly differentiated squamous cell carcinoma of the esophagus. MANAGEMENT: The stenosis was treated with endoscopic dilatations and brachytherapy, but persisted and became a tracheoesophageal fistula despite repeated placement of esophageal stents. Definitive surgical treatment comprised combined transabdominal and thoracic esophagectomy with creation of a gastric tube and cervical esophagogastrostomy, and repair of the trachea with a pericardial patch and intercostal muscle flap. |
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Authors:
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Jeroen Hagendoorn; Marguerite E I Schipper; Arjan Cloïn; Faiz Z Ramjankhan; Peter D Siersema; Richard van Hillegersberg |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2010-11-09 |
Journal Detail:
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Title: Nature reviews. Gastroenterology & hepatology Volume: 7 ISSN: 1759-5053 ISO Abbreviation: Nat Rev Gastroenterol Hepatol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-02 Completed Date: 2011-03-25 Revised Date: 2011-07-19 |
Medline Journal Info:
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Nlm Unique ID: 101500079 Medline TA: Nat Rev Gastroenterol Hepatol Country: England |
Other Details:
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Languages: eng Pagination: 702-6 Citation Subset: IM |
Affiliation:
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Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Squamous Cell
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etiology*,
pathology Education, Medical, Continuing Esophageal Neoplasms / etiology*, pathology Fatal Outcome Female Hodgkin Disease / radiotherapy* Humans Middle Aged Neoplasms, Radiation-Induced / etiology*, pathology Radiotherapy / adverse effects* Tracheoesophageal Fistula / etiology*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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