Document Detail


A patient with systemic lupus erythematosus who developed massive small intestinal hemorrhaging during treatment for chronic lupus peritonitis.
MedLine Citation:
PMID:  21761227     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A 50-year-old Japanese woman, a patient with systemic lupus erythematosus (SLE) complicated with chronic lupus peritonitis, developed massive small intestinal hemorrhaging. She was treated with intravenous pulse of methylprednisolone, intravenous pulse of cyclophosphamide (IVCY), and immunoabsorption, but the peritonitis was refractory to these treatments. Subsequently, she was treated with oral corticosteroid and tacrolimus, and received IVCY monthly, but she developed massive small intestinal hemorrhaging 1 year after. Abdominal angiography detected multiple bleeding sites from the jejunal and ileal arteries. After transarterial embolization treatment, the melena disappeared. The pathology of this case appeared to be lupus mesenteric vasculitis.
Authors:
Shin-Ya Kawashiri; Ayako Nishino; Eijun Sueyoshi; Akitomo Okada; Tomohiro Koga; Satoshi Yamasaki; Hideki Nakamura; Tomoki Origuchi; Atsushi Kawakami
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-15
Journal Detail:
Title:  Modern rheumatology / the Japan Rheumatism Association     Volume:  -     ISSN:  1439-7609     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100959226     Medline TA:  Mod Rheumatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan, shin-ya@hotmail.co.jp.
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