Document Detail

A patient with myoclonic epilepsy in infancy followed by myoclonic astatic epilepsy.
MedLine Citation:
PMID:  22342656     Owner:  NLM     Status:  Publisher    
Myoclonic epilepsy in infancy (MEI) is a primary generalized epilepsy. According to the literature, the outcome of MEI is usually benign. Here we report a patient who developed myoclonic astatic epilepsy at age four, having been seizure free without antiepileptic drug treatment for 2 years after his recovery from MEI. At age four, a video-EEG-recording showed frequent head nodding (atonic seizures) and myoclonic astatic seizures associated with diffuse spikes or polyspikes and waves. The interictal EEG revealed frequent bursts of generalized 100-200μV, 2-4Hz spike-and-slow-wave complexes. Despite a general favorable outcome, more severe epilepsy syndromes may develop after MEI, and mental retardation is sometimes observed. Our case and the previous literature suggest that epilepsies following on from MEI often involve myoclonic seizures.
Stéphane Auvin; Marie-Dominique Lamblin; Jean-Christophe Cuvellier; Louis Vallée
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-16
Journal Detail:
Title:  Seizure : the journal of the British Epilepsy Association     Volume:  -     ISSN:  1532-2688     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306979     Medline TA:  Seizure     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
APHP, Hôpital Robert Debré, Service de Neurologie Pédiatrique, Paris, France; Inserm, U676, Paris, France; Univ Paris Diderot, Sorbonne Paris Cité, INSERM UMR676, Paris, France.
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