Document Detail


A patient with a large recurrent pheochromocytoma demonstrating the pitfalls of diagnosis.
MedLine Citation:
PMID:  21894215     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background. A 59-year-old man presented for a follow-up, 6 years after surgery for a large pheochromocytoma. He had suffered from diabetes mellitus, hypertension and abdominal pain in the right flank region. Previous postoperative follow-up did not reveal tumor recurrence.Investigation. Measurement of plasma free metanephrine and normetanephrine by high-performance liquid chromatography and radioimmunoassay; 123I-metaiodobenzylguanidine (MIBG) scintigraphy; hybrid 123I-MIBG single-photon emission CT (SPECT)-CT; MRI; testing for plasma norepinephrine and epinephrine; intraoperative ultrasonography; histological staining for chromogranin A and synaptophysin; and postoperative 18F-dihydroxyphenylalanine (DOPA) PET scan.Diagnosis. Recurrent pheochromocytoma.Management. Laparotomy with tumor resection. Reduction of antihypertensive medications. Further follow-up by MRI, hybrid 123I-MIBG SPECT-CT and testing for plasma catecholamines and free metanephrines.
Authors:
Jörg Singer; Christian A Koch; Woubet Kassahun; Peter Lamesch; Graeme Eisenhofer; Regine Kluge; Thomas Lincke; Matthias Seiwerts; Gudrun Borte; Katrin Schierle; Ralf Paschke;
Related Documents :
21852905 - Evaluation of portal venous velocity with doppler ultrasound in patients with nonalcoho...
10065185 - Role of mri in the diagnosis of cervical brucellar spondylitis: case report.
413395 - Computed tomographic brain scanning in intraparenchymal pyogenic abscesses.
7291515 - Computed tomography of the lesser peritoneal sac.
2022985 - Indium-111-leukocyte imaging in acute cholecystitis.
6288505 - Diagnostic ability of hepatobiliary scintigraphy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-06
Journal Detail:
Title:  Nature reviews. Endocrinology     Volume:  -     ISSN:  1759-5037     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101500078     Medline TA:  Nat Rev Endocrinol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Antiresorptive therapies for osteoporosis: a clinical overview.
Next Document:  Gastroesophageal Reflux Symptoms and Comorbid Asthma and Posttraumatic Stress Disorder Following the...