Document Detail


A patient with congenital lipoid adrenal hyperplasia evaluated by serial abdominal ultrasonography.
MedLine Citation:
PMID:  9686812     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adrenal enlargement was followed by serial ultrasonography in an infant with congenital lipoid adrenal hyperplasia (lipoid CAH) from day 12 until 2 years and 4 months of age, when they were no longer detectable. Contrary to other types of CAH in which the configuration changes soon after replacement therapy, this infant with lipoid CAH showed persistent adrenal cortex enlargement due to massive accumulation of lipids and cholesterol resulting in a damaged glandular cyto-architecture. CONCLUSION: ultrasonographically persistent enlargement of the adrenals after replacement therapy is suggestive of the lipoid form of CAH.
Authors:
J Takaya; R Ishihara; M Kino; H Higashino; Y Kobayashi
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pediatrics     Volume:  157     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-09-22     Completed Date:  1998-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  544-6     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Kansai Medical University, Moriguchi, Osaka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex / ultrasonography*
Adrenal Hyperplasia, Congenital / genetics,  physiopathology,  ultrasonography*
DNA Mutational Analysis
Female
Humans
Infant
Lipid Metabolism

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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