Document Detail

A patient with Takayasu's arteritis and rheumatoid arthritis who responded to tacrolimus hydrate.
MedLine Citation:
PMID:  18025771     Owner:  NLM     Status:  MEDLINE    
We encountered the rare case of a 50-year-old woman who developed rheumatoid arthritis (RA) while suffering from Takayasu's arteritis of arch vessel type. prednisolone (PSL) therapy was continued at a maintenance dose of 7.5 mg due to recurring inflammation. She was affected with RA for 7 years after Takayasu's arteritis. Disease-modifying antirheumatic drugs (DMARDs) were unusable because of side effects. In the summer of 2005, RA activity increased, and treatment with tacrolimus hydrate at 1.5 mg was started; thereafter, the activity of RA and Takayasu's arteritis was relieved, especially MRA findings. We report that therapy with tacrolimus hydrate markedly relieved two disorders, and review the literature.
Isamu Yokoe; Hitomi Haraoka; Hideaki Harashima
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2007-11-16
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  46     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-20     Completed Date:  2007-12-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1873-7     Citation Subset:  IM    
Department of Internal Medicine, Itabashi Medical Center Hospital, Tokyo.
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MeSH Terms
Arthritis, Rheumatoid / complications,  drug therapy*,  radiography
Immunosuppressive Agents / therapeutic use*
Middle Aged
Tacrolimus / therapeutic use*
Takayasu Arteritis / complications,  drug therapy*,  radiography
Reg. No./Substance:
0/Immunosuppressive Agents; 109581-93-3/Tacrolimus

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