Document Detail

A patient care system for early 3.0 Tesla magnetic resonance imaging of very low birth weight infants.
MedLine Citation:
PMID:  19926413     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Very low birth weight (VLBW) infants (weight <1500 g) are increasingly cared for without prolonged periods of positive pressure ventilation (PPV).
AIMS: To develop a system for 3.0 T magnetic resonance (MR) image acquisition from VLBW infants who are not receiving PPV, and to test the clinical stability of a consecutive cohort of such infants.
DESIGN: Seventy VLBW infants whose median weight at image acquisition was 940 g (590-1490) underwent brain MR imaging with the developed care system as participants in research. Twenty infants (29%) received nasal continuous positive airway pressure (nCPAP), 28 (40%) received supplemental oxygen by nasal cannulae, and 22 (31%) breathed spontaneously in air during the MR examination.
RESULTS: There were no significant adverse events. Seventy-six percent had none or transient self-correcting oxygen desaturations. Desaturations that required interruption of the scan for assessment were less common among infants receiving nCPAP (2/20) or breathing spontaneously in air (2/22), compared with those receiving nasal cannulae oxygen (13/28), p=0.003. Sixty-four (91%) infants had an axillary temperature > or =36 degrees C at completion of the scan (lowest 35.7 degrees C), There was no relationship between weight (p=0.167) or use of nCPAP (p=0.453) and axillary temperature <36 degrees C. No infant became hyperthermic.
CONCLUSION: VLBW infants who do not require ventilation by endotracheal tube can be imaged successfully and safely at 3.0 T, including those receiving nCPAP from a customised system.
N Merchant; A Groves; D J Larkman; S J Counsell; M A Thomson; V Doria; M Groppo; T Arichi; S Foreman; D J Herlihy; J V Hajnal; L Srinivasan; A Foran; M Rutherford; A D Edwards; J P Boardman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-11-17
Journal Detail:
Title:  Early human development     Volume:  85     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-01     Completed Date:  2010-02-01     Revised Date:  2014-02-19    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  779-83     Citation Subset:  IM    
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MeSH Terms
Birth Weight / physiology
Continuity of Patient Care
Infant, Newborn
Infant, Premature / physiology
Infant, Very Low Birth Weight*
Intensive Care, Neonatal / methods
Intubation, Intratracheal
Magnetic Resonance Imaging / adverse effects,  instrumentation,  methods*
Oxygen Inhalation Therapy / methods
Patient Care Team / organization & administration
Patient Positioning / methods
Patient-Centered Care / methods*
Positive-Pressure Respiration / methods
Grant Support
G0502100//Medical Research Council; G0701896//Medical Research Council; MC_U120061309//Medical Research Council; MC_U120081323//Medical Research Council; MC_U120088465//Medical Research Council; //Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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