| A patient care system for early 3.0 Tesla magnetic resonance imaging of very low birth weight infants. | |
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MedLine Citation:
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PMID: 19926413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Very low birth weight (VLBW) infants (weight <1500 g) are increasingly cared for without prolonged periods of positive pressure ventilation (PPV). AIMS: To develop a system for 3.0 T magnetic resonance (MR) image acquisition from VLBW infants who are not receiving PPV, and to test the clinical stability of a consecutive cohort of such infants. DESIGN: Seventy VLBW infants whose median weight at image acquisition was 940 g (590-1490) underwent brain MR imaging with the developed care system as participants in research. Twenty infants (29%) received nasal continuous positive airway pressure (nCPAP), 28 (40%) received supplemental oxygen by nasal cannulae, and 22 (31%) breathed spontaneously in air during the MR examination. RESULTS: There were no significant adverse events. Seventy-six percent had none or transient self-correcting oxygen desaturations. Desaturations that required interruption of the scan for assessment were less common among infants receiving nCPAP (2/20) or breathing spontaneously in air (2/22), compared with those receiving nasal cannulae oxygen (13/28), p=0.003. Sixty-four (91%) infants had an axillary temperature > or =36 degrees C at completion of the scan (lowest 35.7 degrees C), There was no relationship between weight (p=0.167) or use of nCPAP (p=0.453) and axillary temperature <36 degrees C. No infant became hyperthermic. CONCLUSION: VLBW infants who do not require ventilation by endotracheal tube can be imaged successfully and safely at 3.0 T, including those receiving nCPAP from a customised system. |
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Authors:
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N Merchant; A Groves; D J Larkman; S J Counsell; M A Thomson; V Doria; M Groppo; T Arichi; S Foreman; D J Herlihy; J V Hajnal; L Srinivasan; A Foran; M Rutherford; A D Edwards; J P Boardman |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-11-17 |
Journal Detail:
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Title: Early human development Volume: 85 ISSN: 1872-6232 ISO Abbreviation: Early Hum. Dev. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-01 Completed Date: 2010-02-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708381 Medline TA: Early Hum Dev Country: Ireland |
Other Details:
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Languages: eng Pagination: 779-83 Citation Subset: IM |
Affiliation:
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Imaging Sciences Department, Division of Clinical Sciences, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight
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physiology Continuity of Patient Care Humans Infant, Newborn Infant, Premature / physiology Infant, Very Low Birth Weight* Intensive Care, Neonatal / methods Intubation, Intratracheal Magnetic Resonance Imaging / adverse effects, instrumentation, methods* Oxygen Inhalation Therapy / methods Patient Care Team / organization & administration Patient Positioning / methods Patient-Centered Care / methods* Positive-Pressure Respiration / methods Safety |
| Grant Support | |
ID/Acronym/Agency:
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//Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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