| The pathophysiology of calcitonin in man. | |
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MedLine Citation:
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PMID: 3781766 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is generally accepted that calcitonin (CT) induces a decrement in cytosolic Ca++, and an increase of cAMP in target cells of several organs and tissues. This happens particularly in bone, where osteoclast activity and size decreases, along with the widely-known hypocalcaemic and hypophosphoraemic effect of the hormone. The physiological role of CT appears to be of importance in pregnancy and perhaps in infancy, when it antagonizes possible excessive bone loss. Some experimental evidence shows that CT may be involved in the maintenance of post-meal calcaemia. It is not yet established whether paucity of CT plays any important role in the pathogenesis of pathological conditions such as post-menopausal and senile osteoporosis. |
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Authors:
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M Passeri; E Palummeri; M Pedrazzoni; G Cervellin; M Barbagallo; L Butturini; R Di Ruvo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of tissue reactions Volume: 8 ISSN: 0250-0868 ISO Abbreviation: Int J Tissue React Publication Date: 1986 |
Date Detail:
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Created Date: 1987-01-16 Completed Date: 1987-01-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8302116 Medline TA: Int J Tissue React Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 255-60 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Calcitonin / blood, physiology*, secretion Disease / physiopathology Female Humans Male Middle Aged Sex Factors |
| Chemical | |
Reg. No./Substance:
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9007-12-9/Calcitonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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