Document Detail


The pathophysiologic basis of acute coronary insufficiency. Observations favoring the hypothesis of intermittent reversible coronary obstruction.
MedLine Citation:
PMID:  910678     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical, coronary angiographic, and myocardial metabolic data were analyzed to test alternative hypotheses for the pathophysiologic basis of acute coronary insufficiency. The initial incidence of coronary collaterals was not low in relation to coexisting coronary obstructive disease; the early subsequent coronary occlusion rate was high; and in asymptomatic intervals during the acute illness, myocardial hypoxia was infrequent and coronary reserve substantial. These observations support the hypothesis that the acute coronary insufficiency syndrome is caused by reversible coronary ischemic episodes rather than by a new permanent atherosclerotic lesion.
Authors:
W A Neill; L W Ritzmann; R Selden
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  94     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  439-44     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Angina Pectoris
Cardiac Pacing, Artificial
Chronic Disease
Collateral Circulation
Coronary Angiography
Coronary Disease / physiopathology*
Coronary Vessels / physiopathology*
Heart / physiopathology
Hemodynamics / drug effects
Humans
Middle Aged
Oxygen / administration & dosage
Prospective Studies
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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