Document Detail


The pathology of large-vessel vasculitides.
MedLine Citation:
PMID:  21586202     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vasculitis affecting large elastic arteries, including the aorta and major proximal branches, encompasses various diseases including Takayasu arteritis, giant cell (or temporal) arteritis, and tertiary syphilis, but also may occur as a rare complication of Behçet's disease, rheumatoid arthritis, sarcoidosis, Cogan syndrome, Kawasaki disease, ankylosing spondylitis, systemic lupus erythematosus and Wegener's granulomatosis. Recent reports have also established a link between inflammatory abdominal aortic aneurysm as well as lymphoplasmacytic thoracic aortitis with an overabundance of IgG4-producing plasma cells and the burgeoning constellation of 'Hyper-IgG4' syndromes. This review focuses on morphologic aspects of large-vessel vasculitis pathology associated with giant cell arteritis, Takayasu arteritis, idiopathic or isolated aortitis, lymphoplasmacytic thoracic and ascending aortitis, and the inflammatory aneurysm/retroperitoneal fibrosis syndrome.
Authors:
Dylan V Miller; Joseph J Maleszewski
Publication Detail:
Type:  Journal Article; Review     Date:  2011-05-11
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  29     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-05-18     Completed Date:  2011-08-23     Revised Date:  2011-09-11    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  S92-8     Citation Subset:  IM    
Affiliation:
Intermountain Medical Center & University of Utah, Murray, USA. dylan.miller@imail.org
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MeSH Terms
Descriptor/Qualifier:
Aorta / immunology,  pathology*
Elastic Tissue / immunology,  pathology*
Giant Cell Arteritis / immunology,  pathology*
Humans
Takayasu Arteritis / immunology,  pathology*

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