| The pathogenesis of Chiari I malformation and syringomyelia. | |
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MedLine Citation:
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PMID: 21513643 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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METHODS: A literature review for articles pertaining to Chiari I malformation or syringomyelia before August 2010 was conducted; in addition, the author's own experience in treating Chiari I malformation and syringomyelia is included. RESULTS: Chiari I malformation has been defined radiographically as cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum. By this narrow definition, Chiari I malformation (i.e. cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum) likely encompasses a heterogeneous grouping of disorders caused by different mechanisms. Molecular and genetic studies have been helpful in furthering our understanding of Chiari I malformation. CONCLUSION: A review of the pathogeneses of Chiari I malformation and syringomyelia is reported. |
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Authors:
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Raymond F Sekula; Gregory D Arnone; Christine Crocker; Khaled M Aziz; Noam Alperin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurological research Volume: 33 ISSN: 1743-1328 ISO Abbreviation: Neurol. Res. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905298 Medline TA: Neurol Res Country: England |
Other Details:
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Languages: eng Pagination: 232-9 Citation Subset: IM |
Affiliation:
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Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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