Document Detail


The participation of shivering and nonshivering thermogenesis in warm and cold-acclimated rats.
MedLine Citation:
PMID:  6128133     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Both shivering and nonshivering thermogenesis are ways of increasing oxygen consumption in the rat. The participation of nonshivering thermogenesis after cold acclimation is well established, but there is little evidence of the relative importance of each kind of thermogenesis in acclimated and nonacclimated rats. 2. Oxygen consumption and rectal temperature were measured in warm and cold-acclimated rats exposed both to cold (10 degrees C) and warm (30 degree C) environments. 3. Shivering was blocked by mephenesin (10 mg/100 g body wt) and nonshivering thermogenesis was blocked by propranolol (0.5 mg/100 g body wt). 4. Control animals were injected with saline (0.5 ml/100 g body wt). 5. The results showed that shivering is not effective in maintaining a constant rectal temperature and that nonshivering thermogenesis does not contribute to the increase in oxygen consumption of warm-acclimated rats exposed to cold.
Authors:
M A Griggio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. A, Comparative physiology     Volume:  73     ISSN:  0300-9629     ISO Abbreviation:  Comp Biochem Physiol A Comp Physiol     Publication Date:  1982  
Date Detail:
Created Date:  1983-01-19     Completed Date:  1983-01-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1276312     Medline TA:  Comp Biochem Physiol A Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  481-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acclimatization* / drug effects
Animals
Body Temperature Regulation* / drug effects
Cold Temperature*
Hot Temperature
Male
Mephenesin / pharmacology
Oxygen Consumption / drug effects
Propranolol / pharmacology
Rats
Rats, Inbred Strains
Shivering* / drug effects
Chemical
Reg. No./Substance:
525-66-6/Propranolol; 59-47-2/Mephenesin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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