Document Detail

Is parotid lymphadenopathy a new disease or part of AIDS?
MedLine Citation:
PMID:  3177755     Owner:  NLM     Status:  MEDLINE    
This report describes a series of 15 patients who presented with masses in the tail of the parotid gland which proved at biopsy to be benign hyperplastic lymphadenopathy similar to lymphoepithelial hyperplasia. There were 11 male and 4 female patients. All had a history of intravenous drug use. Ten patients complained of pain. Six patients had smaller masses on the contralateral side of the gland, whereas seven patients had minor axillary adenopathy. Needle aspiration was performed in 12 patients; although not conclusively diagnostic, it ruled out primary salivary tumors. Thick purulent material was aspirated in five patients. All 15 patients underwent parotid exploration. It was apparent after raising the flap that the disease was related to intraparotid and periparotid lymph nodes. Lymphadenopathy in the jugular region, which was not appreciated preoperatively, was also noted in all patients. Each patient underwent exposure of the main trunk of the facial nerve and limited superficial parotidectomy. The postoperative course in each patient was uneventful and no patient had a facial nerve deficit. Cerebral toxoplasmosis developed in one patient who died 3 months after surgery; AIDS developed in one other patient. Human immunodeficiency virus (HIV) titers were not performed routinely because none of the patients came for regular follow-up. None of these patients demonstrated lymphoma at the time of this procedure. Parotid lymphadenopathy, which occurs primarily in intravenous drug users, appears to be an early manifestation of pre-AIDS or AIDS-related complex. If patients have no other sizable lymphadenopathy for biopsy, we advocate exploration of the parotid region and excision of periparotid and intraparotid lymph nodes.
A Shaha; W Thelmo; B M Jaffe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  156     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1988-11-15     Completed Date:  1988-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  297-300     Citation Subset:  AIM; IM; X    
Department of Surgery, State University of New York Health Science Center, Brooklyn.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications,  pathology*
Lymph Node Excision
Lymphatic Diseases / complications,  pathology*,  surgery
Parotid Diseases / complications,  pathology*,  surgery
Comment In:
Am J Surg. 1990 Feb;159(2):270-1   [PMID:  2301725 ]

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