Document Detail


The parental origin of de novo X-autosome translocations in females with Duchenne muscular dystrophy revealed by M27 beta methylation analysis.
MedLine Citation:
PMID:  2272503     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The parental origin of 3 de novo X-autosome translocations in females with Duchenne Muscular Dystrophy (DMD) was studied by means of methylation analysis using the X-linked probe M27 beta. In all three the translocation was found to be paternal in origin. The parental origin of X-autosome translocations in females with and without DMD is compared with other structural abnormalities of the X and with autosomal translocations.
Authors:
D O Robinson; Y Boyd; D Cockburn; M N Collinson; I Craig; P A Jacobs
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Genetical research     Volume:  56     ISSN:  0016-6723     ISO Abbreviation:  Genet. Res.     Publication Date:    1990 Oct-Dec
Date Detail:
Created Date:  1991-02-22     Completed Date:  1991-02-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370741     Medline TA:  Genet Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  135-40     Citation Subset:  IM    
Affiliation:
Wessex Regional Genetics Laboratory, General Hospital, Salisbury.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blotting, Southern
Cell Line
Female
Humans
Hybrid Cells
Methylation
Mice
Muscular Dystrophies / genetics*
Translocation, Genetic*
X Chromosome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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