Document Detail

A paradigm for quantifying ventricular contraction.
MedLine Citation:
PMID:  12097979     Owner:  NLM     Status:  MEDLINE    
The left ventricle may be described as a time, volume and flow dependent pressure generator. First, isovolumic pressure is measured at various end-diastolic volumes. Next, pressure is adjusted to account for small changes accompanying ejection, denoted the ejection effect. The resulting analytical function can describe pressure generation and ventricular outflow of the ventricle under a wide range of contractile and vascular conditions. This paradigm is unique in separating isovolumic from ejecting ventricular properties, as well as ventricular from vascular conditions.
Joseph L Palladino; Abraham Noordergraaf
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Publication Detail:
Type:  Lectures    
Journal Detail:
Title:  Cellular & molecular biology letters     Volume:  7     ISSN:  1425-8153     ISO Abbreviation:  Cell. Mol. Biol. Lett.     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-04     Completed Date:  2002-10-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9607427     Medline TA:  Cell Mol Biol Lett     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  331-5     Citation Subset:  IM    
Department of Engineering, Trinity College, Hartford, CT, USA.
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MeSH Terms
Models, Cardiovascular
Myocardial Contraction / physiology*
Ventricular Function*
Ventricular Pressure / physiology

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