| Is pH a biochemical marker of IQ? | |
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MedLine Citation:
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PMID: 8805839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have measured intracellular brain pH in vivo in 42 boys and found a significant correlation between this biochemical parameter and samples of intelligent behaviour. To the best of our knowledge this is the first reported relation between a biochemical marker which is within normal physiological values and intellectual ability. pH is one of the most accurate parameters that can be measured by 31P magnetic resonance spectroscopy and it reflects sensitively cellular ionic status and metabolic activity. The observed correlation, although not implying a causal relation, raises the possibility that intelligent behaviour may be influenced by the ionic status of brain tissue, or vice versa. |
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Authors:
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C Rae; R B Scott; C H Thompson; G J Kemp; I Dumughn; P Styles; I Tracey; G K Radda |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Proceedings. Biological sciences / The Royal Society Volume: 263 ISSN: 0962-8452 ISO Abbreviation: Proc. Biol. Sci. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-12-05 Completed Date: 1996-12-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101245157 Medline TA: Proc Biol Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1061-4 Citation Subset: IM |
Affiliation:
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MRC Biochemical and Clinical Magnetic Resonance Spectroscopy Unit, John Radcliffe Hospital, Headington, Oxford, U.K. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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physiology* Child Humans Hydrogen-Ion Concentration Intelligence / physiology* Male Wechsler Scales |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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