Document Detail


Is pH a biochemical marker of IQ?
MedLine Citation:
PMID:  8805839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have measured intracellular brain pH in vivo in 42 boys and found a significant correlation between this biochemical parameter and samples of intelligent behaviour. To the best of our knowledge this is the first reported relation between a biochemical marker which is within normal physiological values and intellectual ability. pH is one of the most accurate parameters that can be measured by 31P magnetic resonance spectroscopy and it reflects sensitively cellular ionic status and metabolic activity. The observed correlation, although not implying a causal relation, raises the possibility that intelligent behaviour may be influenced by the ionic status of brain tissue, or vice versa.
Authors:
C Rae; R B Scott; C H Thompson; G J Kemp; I Dumughn; P Styles; I Tracey; G K Radda
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Proceedings. Biological sciences / The Royal Society     Volume:  263     ISSN:  0962-8452     ISO Abbreviation:  Proc. Biol. Sci.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-12-05     Completed Date:  1996-12-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101245157     Medline TA:  Proc Biol Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1061-4     Citation Subset:  IM    
Affiliation:
MRC Biochemical and Clinical Magnetic Resonance Spectroscopy Unit, John Radcliffe Hospital, Headington, Oxford, U.K.
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MeSH Terms
Descriptor/Qualifier:
Brain / physiology*
Child
Humans
Hydrogen-Ion Concentration
Intelligence / physiology*
Male
Wechsler Scales

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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