Document Detail

Is oxytocin given during surgical termination of first trimester pregnancy useful? A randomized controlled trial.
MedLine Citation:
PMID:  21241263     Owner:  NLM     Status:  In-Data-Review    
Objective. To compare the impact of 5 IU (international units) of oxytocin administered during surgical termination of first-trimester pregnancy compared to no oxytocin, on postoperative bleeding, pain and nausea. Design. A randomized controlled single-blinded study. Setting. A Norwegian community hospital with 1,064 consecutive legal abortions in the 20 months of study period. Sample. A total of 378 women undergoing surgical termination of first-trimester pregnancy and willing to participate in the study Methods. Women were randomized into two groups: Group 1, receiving a standard procedure of 5 IU of oxytocin during the surgical procedure, or Group 2, receiving no oxytocic agent. All women had preoperative misoprostol. Main Outcome Measures. Vaginal bleeding, pain and nausea recorded by weighing pads immediately after the surgical procedure and counting pads during the three following days. Results. No significant differences between the two groups could be demonstrated with regard to the recorded postoperative blood loss, pain and nausea. Conclusions. The standard routine of administering oxytocin during surgical termination of first-trimester pregnancy should be revised.
Ingerid Helene Herstad Nygaard; Annelill Valbø; Helene Christine Heide; Milena Kresovic
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Publication Detail:
Type:  Journal Article     Date:  2010-12-02
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  90     ISSN:  1600-0412     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  England    
Other Details:
Languages:  eng     Pagination:  174-8     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2010 Nordic Federation of Societies of Obstetrics and Gynecology.
Department of Gynecology and Obstetrics, Asker and Baerum Hospital, Norway.
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