| An overview of mortality and sequelae of preterm birth from infancy to adulthood. | |
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MedLine Citation:
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PMID: 18207020 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Survival rates have greatly improved in recent years for infants of borderline viability; however, these infants remain at risk of developing a wide array of complications, not only in the neonatal unit, but also in the long term. Morbidity is inversely related to gestational age; however, there is no gestational age, including term, that is wholly exempt. Neurodevelopmental disabilities and recurrent health problems take a toll in early childhood. Subsequently hidden disabilities such as school difficulties and behavioural problems become apparent and persist into adolescence. Reassuringly, however, most children born very preterm adjust remarkably well during their transition into adulthood. Because mortality rates have fallen, the focus for perinatal interventions is to develop strategies to reduce long-term morbidity, especially the prevention of brain injury and abnormal brain development. In addition, follow-up to middle age and beyond is warranted to identify the risks, especially for cardiovascular and metabolic disorders that are likely to be experienced by preterm survivors. |
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Authors:
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Saroj Saigal; Lex W Doyle |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Lancet Volume: 371 ISSN: 1474-547X ISO Abbreviation: Lancet Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-21 Completed Date: 2008-01-31 Revised Date: 2008-03-27 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: England |
Other Details:
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Languages: eng Pagination: 261-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Paediatrics, McMaster University, Hamilton, ON, Canada. saigal@mcmaster.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Developed Countries Female Follow-Up Studies Gestational Age* Humans Infant Infant Mortality / trends* Infant, Newborn Infant, Premature Infant, Premature, Diseases / epidemiology, mortality*, physiopathology Intensive Care Units, Neonatal / economics Male Survival Rate |
| Comments/Corrections | |
Comment In:
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Lancet. 2008 Mar 15;371(9616):897-8
[PMID:
18342681
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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