| The outcome of twin reversed arterial perfusion sequence diagnosed in the first trimester. | |
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MedLine Citation:
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PMID: 20522408 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to document the mortality of twin reversed arterial perfusion (TRAP) sequence from the first trimester to planned intervention at 16-18 weeks. STUDY DESIGN: A retrospective review was performed of the outcome of monochorionic twin pregnancies diagnosed with twin reversed arterial perfusion sequence in the first trimester. RESULTS: Twenty-six pregnancies were diagnosed with twin reversed arterial perfusion sequence in the first trimester: 2 opted for termination of pregnancy and 24 opted for prophylactic intervention to arrest the reversed flow, which was planned at 16-18 weeks. In 8 of 24 (33%) pregnancies, spontaneous death of the pump twin occurred between diagnosis and planned intervention. In 5 of 24 (21%), there was a spontaneous arrest of flow; whereas, in 11 (46%) there was persistent flow toward the acardiac twin at 16-18 weeks. CONCLUSION: Twin reversed arterial perfusion carries a high mortality between the first and early second trimester. |
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Authors:
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Liesbeth Lewi; Catalina Valencia; Esperanza Gonzalez; Jan Deprest; Kypros H Nicolaides |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-03 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 203 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-06 Completed Date: 2010-09-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 213.e1-4 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010. Published by Mosby, Inc. |
Affiliation:
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Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced
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statistics & numerical data Abortion, Spontaneous / epidemiology Adult Female Fetal Death / epidemiology Fetofetal Transfusion / diagnosis*, mortality*, surgery Fetoscopy Humans Laser Coagulation Live Birth / epidemiology Pregnancy Pregnancy Trimester, First* Retrospective Studies Twins Umbilical Cord / surgery, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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