Document Detail

The outcome of preterm neonates with intraventricular hemorrhage delivered with intravenous meperidine or epidural analgesia.
MedLine Citation:
PMID:  17285424     Owner:  NLM     Status:  MEDLINE    
We aimed to study, retrospectively, the neonatal outcome of 45 preterm neonates with intraventricular hemorrhage (IVH) who were delivered vaginally with intravenous meperidine (n = 23) or epidural analgesia (n = 22). Neonates in the epidural group had a better outcome in terms of a first-minute Apgar score of 7 or less, in 31% vs 69% (P = 0.001); 5-min Apgar score of 7 or less, in 18% vs 82% (P = 0.003); a lower incidence of respiratory distress syndrome (RDS; 23% vs 30%; P = 0.03); a lower dopamine requirement during the first neonatal week (13% vs 72%; P = 0.01); and a higher survival rate (91% vs 58%, respectively; P = 0.008). It is concluded that preterm neonates with IVH had a better outcome when delivered to mothers receiving epidural analgesia as compared to those receiving intravenous meperidine.
Shmuel Evron; Tiberiu Ezri; Nugzar Rigini; Andre Gomel; Peter Szmuk; Oscar Sadan; David Kohelet
Related Documents :
673554 - Early increase in intracranial pressure in preterm infants.
12072694 - S100b protein is increased in asphyxiated term infants developing intraventricular hemo...
22296304 - Risk factors affecting tests of infant motor performance (timp) in pre-term infants at ...
20713284 - Clinical manifestations of symptomatic intracranial hemorrhage in term neonates: 18 yea...
1582374 - Bioelectric brain maturation in fullterm infants and in healthy and pathological preter...
20182434 - Echocardiographic predictors of symptomatic patent ductus arteriosus in extremely-low-b...
Publication Detail:
Type:  Journal Article     Date:  2007-01-30
Journal Detail:
Title:  Journal of anesthesia     Volume:  21     ISSN:  0913-8668     ISO Abbreviation:  J Anesth     Publication Date:  2007  
Date Detail:
Created Date:  2007-02-07     Completed Date:  2007-04-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905667     Medline TA:  J Anesth     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  90-3     Citation Subset:  IM    
Obstetric Anesthesia Unit, Department of Anesthesia, Edith Wolfson Medical Center, Holon, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analgesia, Epidural / adverse effects*,  methods
Analgesics, Opioid / administration & dosage,  adverse effects
Anesthesia, Intravenous / adverse effects*,  methods
Anesthesia, Obstetrical / adverse effects*,  methods
Anesthetics, Local / administration & dosage,  adverse effects
Apgar Score
Bupivacaine / administration & dosage,  adverse effects
Cerebral Hemorrhage / epidemiology*
Cerebral Ventricles
Dopamine / administration & dosage
Dopamine Agents / administration & dosage
Infant, Newborn
Infant, Premature*
Meperidine / administration & dosage,  adverse effects*
Respiratory Distress Syndrome, Newborn / epidemiology
Retrospective Studies
Risk Factors
Survival Rate
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anesthetics, Local; 0/Dopamine Agents; 2180-92-9/Bupivacaine; 57-42-1/Meperidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of magnesium sulfate on neuromuscular function and spontaneous breathing during sevoflurane ...
Next Document:  Comparison of the effects of fentanyl and remifentanil on splanchnic tissue perfusion during cardiac...