| The outcome of preterm neonates with intraventricular hemorrhage delivered with intravenous meperidine or epidural analgesia. | |
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MedLine Citation:
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PMID: 17285424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We aimed to study, retrospectively, the neonatal outcome of 45 preterm neonates with intraventricular hemorrhage (IVH) who were delivered vaginally with intravenous meperidine (n = 23) or epidural analgesia (n = 22). Neonates in the epidural group had a better outcome in terms of a first-minute Apgar score of 7 or less, in 31% vs 69% (P = 0.001); 5-min Apgar score of 7 or less, in 18% vs 82% (P = 0.003); a lower incidence of respiratory distress syndrome (RDS; 23% vs 30%; P = 0.03); a lower dopamine requirement during the first neonatal week (13% vs 72%; P = 0.01); and a higher survival rate (91% vs 58%, respectively; P = 0.008). It is concluded that preterm neonates with IVH had a better outcome when delivered to mothers receiving epidural analgesia as compared to those receiving intravenous meperidine. |
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Authors:
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Shmuel Evron; Tiberiu Ezri; Nugzar Rigini; Andre Gomel; Peter Szmuk; Oscar Sadan; David Kohelet |
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Publication Detail:
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Type: Journal Article Date: 2007-01-30 |
Journal Detail:
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Title: Journal of anesthesia Volume: 21 ISSN: 0913-8668 ISO Abbreviation: J Anesth Publication Date: 2007 |
Date Detail:
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Created Date: 2007-02-07 Completed Date: 2007-04-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8905667 Medline TA: J Anesth Country: Japan |
Other Details:
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Languages: eng Pagination: 90-3 Citation Subset: IM |
Affiliation:
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Obstetric Anesthesia Unit, Department of Anesthesia, Edith Wolfson Medical Center, Holon, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analgesia, Epidural / adverse effects*, methods Analgesics, Opioid / administration & dosage, adverse effects Anesthesia, Intravenous / adverse effects*, methods Anesthesia, Obstetrical / adverse effects*, methods Anesthetics, Local / administration & dosage, adverse effects Apgar Score Bupivacaine / administration & dosage, adverse effects Cerebral Hemorrhage / epidemiology* Cerebral Ventricles Comorbidity Dopamine / administration & dosage Dopamine Agents / administration & dosage Female Humans Incidence Infant, Newborn Infant, Premature* Meperidine / administration & dosage, adverse effects* Mothers Pregnancy Respiratory Distress Syndrome, Newborn / epidemiology Retrospective Studies Risk Factors Survival Rate |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 0/Anesthetics, Local; 0/Dopamine Agents; 2180-92-9/Bupivacaine; 57-42-1/Meperidine |
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