Document Detail

The outcome of clinical pregnancies following intracytoplasmic sperm injection is not affected by semen quality.
MedLine Citation:
PMID:  9629429     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to investigate the impact of severe oligoasthenoteratozoospermia (OAT) on pregnancy outcome. For this purpose 279 consecutive intracytoplasmic sperm injection (i.c.s.i) cycles were retrospectively evaluated and compared to 436 consecutive IVF cycles performed during the same time frame. Group A (n = 62) included ICSI patients with severe OAT; group B (n = 217) included patients who underwent ICSI for other indications; and group C (n = 436) included couples who underwent standard IVF. The mean age of female patients and mean number of embryos transferred were comparable in all groups. No difference was observed regarding implantation, clinical pregnancy, delivery and miscarriage rates between all three groups, but fertilization rate was significantly lower in group A than in groups B and C. It is concluded that couples undergoing ICSI with severe male infertility (OAT) have a slightly reduced fertilization rate but their chances of delivery and pregnancy loss are similar to those of other patients undergoing clinical ICSI and IVF with non-male infertility.
R Mercan; S E Lanzendorf; J Mayer; A Nassar; S J Muasher; S Oehninger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Andrologia     Volume:  30     ISSN:  0303-4569     ISO Abbreviation:  Andrologia     Publication Date:    1998 Mar-Apr
Date Detail:
Created Date:  1998-08-28     Completed Date:  1998-08-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0423506     Medline TA:  Andrologia     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Howard and Georgeanna Jones Institute for Women's Health, Department of Obstetrics and Gynecology Eastern Virginia Medical School, Norfolk, USA.
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MeSH Terms
Abortion, Spontaneous
Embryo Transfer
Fertilization in Vitro / methods*
Infertility, Male*
Pregnancy Outcome*
Semen / physiology*

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