| An outbreak of vitamin D deficiency rickets in a susceptible population. | |
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MedLine Citation:
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PMID: 574626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nutritional, racial, cultural, and environmental factors have combined to produce a resurgence of vitamin D deficiency rickets in urban Philadelphia. Between January 1974 and June 1978, 24 cases were diagnosed at the Children's Hospital of Philadelphia. Patients' ages ranged from 4 to 58 months. Presenting complaints included seizures, swollen wrists, pathologic fractures, and developmental regression. Sixteen patients were below the third percentile for length and weight. Laboratory results indicated vitamin D deficiency in nursing mothers as well as in infants. All infants had been breast-fed and all were black. Ingestion of vitamin D was limited by exclusion of meat and/or dairy products in 21, and no infants had consistently taken supplemental vitamins. Nineteen were members of Muslim or Seventh Day Adventist faiths. Endogenous synthesis of vitamin D was limited by dark skin, by dressing in long garments with hoods and veils, and by air pollution in a densely populated northern city. The return to a more "natural" diet, free of food additives, has been accompanied by the return of a classic disease of industrial society. Effective management required patience and respect for religious convictions. With treatment, there was correction of chemical and skeletal abnormalities, but few patients showed catch-up growth. |
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Authors:
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S Bachrach; J Fisher; J S Parks |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pediatrics Volume: 64 ISSN: 0031-4005 ISO Abbreviation: Pediatrics Publication Date: 1979 Dec |
Date Detail:
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Created Date: 1980-02-26 Completed Date: 1980-02-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 871-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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African Americans Animals Breast Feeding Cattle Child, Preschool Disease Outbreaks* Disease Susceptibility Female Food Habits Humans Infant Islam Male Milk Pennsylvania Rickets / diagnosis, epidemiology*, etiology Urban Population Vitamin D / therapeutic use |
| Chemical | |
Reg. No./Substance:
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1406-16-2/Vitamin D |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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