Document Detail

An outbreak of shingles?
MedLine Citation:
PMID:  2865576     Owner:  NLM     Status:  MEDLINE    
7 of 101 staff within one department of a large office complex had shingles, as diagnosed by a general practitioner, within a three-month period. This incidence was significantly greater than that in the remaining workforce. Varicella-zoster-specific IgM antibody was detected in all 4 cases from whom early convalescent serum samples were obtained but in none of 22 controls. Within the index department there was evidence of clustering in time and by work area. A case/control study showed that a recent preceeding illness might have been a risk factor for shingles in the outbreak cases, but not for sporadic cases in other departments of the same office complex. This outbreak suggests that shingles can be provoked by reexposure to varicella-zoster virus.
S R Palmer; E O Caul; D E Donald; W Kwantes; H Tillett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-12     Completed Date:  1985-12-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1108-11     Citation Subset:  AIM; IM    
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MeSH Terms
Antibodies, Viral / analysis
Disease Outbreaks*
Herpes Zoster / diagnosis,  epidemiology*,  transmission
Herpesvirus 3, Human / immunology
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Middle Aged
Space-Time Clustering
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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