Document Detail

An outbreak of norovirus infection in a long-term-care unit in Spain.
MedLine Citation:
PMID:  15796277     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Norovirus belongs to the Caliciviridae family and causes outbreaks of infectious enteritis by fecal-oral transmission. In Spain, there have been few outbreaks reported due to this virus. We describe an outbreak on a long-term-care hospital ward. METHODS: Cases were classified as probable, confirmed, and secondary. Stool cultures were performed. Polymerase chain reaction detection of norovirus was also performed. RESULTS: The outbreak occurred from December 7 to 28, 2001, involving 60 cases (32 patients, 19 staff members, 8 patients' relatives, and 1 relative of a staff member). Most (82%) of the cases were female. The most frequently involved ages were 20 to 39 years for staff members and 70 to 89 years for patients. The incubation period of secondary cases in patients' families had a median of 48 hours (range, 1 to 7 days). Clinical symptoms included diarrhea (85%), vomiting (75%), fever (37%), nausea (23%), and abdominal pain (12%). Median duration of the disease was 48 hours (range, 1 to 7 days). All cases resolved and the outbreak halted with additional hygienic measures. Stool cultures were all negative for enteropathogenic bacteria and rotaviruses. In 16 of 23 cases, the norovirus genotype 2 antigen was detected. CONCLUSION: This outbreak of gastroenteritis due to norovirus genotype 2 affected patients, staff members, and their relatives in a long-term-care facility and was controlled in 21 days.
Gemma Navarro; Rosa M Sala; Ferran Segura; César Arias; Esperanza Anton; Pilar Varela; Pilar Peña; Teresa Llovet; Isabel Sanfeliu; Maria Canals; Guadalupe Serrate; Antonio Nogueras
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America     Volume:  26     ISSN:  0899-823X     ISO Abbreviation:  Infect Control Hosp Epidemiol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-30     Completed Date:  2005-12-08     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8804099     Medline TA:  Infect Control Hosp Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM; N    
Unitat d'Epidemiologia I Avaluacio, Corporacio Parc Tauli, Parc Tauli s/n, 08208 Sabadell, Barcelona, Spain.
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MeSH Terms
Caliciviridae Infections / diagnosis,  epidemiology,  transmission*
Cross Infection / prevention & control,  virology*
Disease Outbreaks*
Feces / virology
Gastroenteritis / prevention & control,  virology
Infectious Disease Transmission, Patient-to-Professional
Long-Term Care
Norovirus / isolation & purification*
Spain / epidemiology

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