Document Detail

The osmotic properties of sulphoethyl-sephadex. A model for cartilage.
MedLine Citation:
PMID:  4634835     Owner:  NLM     Status:  MEDLINE    
1. Observations are reported on the variation of the swelling of sulphoethyl-Sephadex C-50 and C-25, and of the partition of NaCl between solution and gel, with the concentration of NaCl. 2. The results were interpreted in terms of Manning's (1969) treatment of the interactions between polyionic polymers and simple electrolytes and of Flory's (1953) treatment of the swelling of gels. 3. The results indicate net inner osmotic pressures as high as 3.6x10(5)Pa (140 mosmolar=3.6x10(5)N/m(2)) in 0.15m-NaCl. 4. It is suggested that cartilage may have net inner osmotic pressure of the order of 10(5)Pa.
A G Ogston; J D Wells
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Biochemical journal     Volume:  128     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1972 Jul 
Date Detail:
Created Date:  1973-01-30     Completed Date:  1973-01-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  685-90     Citation Subset:  IM    
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MeSH Terms
Models, Biological*
Osmotic Pressure
Sodium Chloride
Reg. No./Substance:
0/Gels; 7647-14-5/Sodium Chloride; 9004-54-0/Dextrans

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