| The origin of life. II: How did it begin? | |
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MedLine Citation:
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PMID: 11382135 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The problem of how a mixture of chemicals can spontaneously transform themselves into even a simple living organism remains one of the great outstanding challenges to science. Various primordial soup theories have been proposed in which chemical self-organization brings about the required level of complexity. Major conceptual obstacles remain, however, such as the emergence of the genetic code, and the "chicken-and-egg" problem concerning which came first: nucleic acids or proteins. Currently fashionable is the so-called RNA world theory, which casts RNA in the role of both chicken and egg. Other theories assume that protein chemistry and even clay crystal life came before nucleic acids. To be fully successful, a theory of biogenesis has to explain not merely the emergence of molecular replication and chemical complexity, but the crucial information content and information processing capabilities of the living cell. |
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Authors:
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P Davies |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science progress Volume: 84 ISSN: 0036-8504 ISO Abbreviation: Sci Prog Publication Date: 2001 |
Date Detail:
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Created Date: 2001-05-30 Completed Date: 2001-06-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0411361 Medline TA: Sci Prog Country: England |
Other Details:
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Languages: eng Pagination: 17-29 Citation Subset: IM |
Affiliation:
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Physics Department, Imperial College London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biogenesis* Humans Nucleic Acids / biosynthesis* Protein Biosynthesis* RNA / biosynthesis |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids; 63231-63-0/RNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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