Document Detail

An optimal polymerization conditions for poly-human placenta hemoglobin with lower mean molecular weight.
MedLine Citation:
PMID:  23363417     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To reduce the mean molecular weight [Formula: see text] and to increase the effective polymerization ratio (REff) of polymerized human placenta hemoglobin (PolyPHb).
METHODS: Three factors of GDA-PolyPHb process such as the approach of feeding GDA (FGDA), hemoglobin concentration ([Hb]) and the molar ratio of GDA, and hemoglobin(RGDA:Hb) were investigated. Finally, the expansion experiments were conducted with optimal conditions.
RESULTS: The data showed that the HBOCs with the REff of 67.35% and lower [Formula: see text] of 162.70 kDa were prepared by optimal conditions.
CONCLUSION: Compared to original process, the optimal process greatly decreased the [Formula: see text] and increased the REff.
Wentao Zhou; Lanzhen Zhao; Jinfeng Wang; Shen Li; Gang Chen; Jiaxin Liu; Chengmin Yang
Related Documents :
12019277 - Validity and reliability of diastolic pulse contour analysis (windkessel model) in humans.
16114677 - Light attenuation parameters for waste stabilisation ponds.
21513717 - Global stability for cholera epidemic models.
1539087 - Toward a reconceptualization of the law of initial value.
23209607 - Multiparametric analysis of cell-free dna in melanoma patients.
16872647 - Computation of the redox and protonation properties of quinones: towards the prediction...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-30
Journal Detail:
Title:  Artificial cells, nanomedicine, and biotechnology     Volume:  41     ISSN:  2169-141X     ISO Abbreviation:  Artif Cells Nanomed Biotechnol     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-09-27     Completed Date:  2014-04-22     Revised Date:  2014-06-24    
Medline Journal Info:
Nlm Unique ID:  101594777     Medline TA:  Artif Cells Nanomed Biotechnol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  289-92     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Transfusion*
Cell-Free System
Complementary Therapies*
Glutaral / chemistry*
Hemoglobins / chemistry*,  metabolism
Molecular Weight
Placenta / metabolism
Reg. No./Substance:
0/Hemoglobins; T3C89M417N/Glutaral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A review of mometasone furoate / formoterol in the treatment of asthma.
Next Document:  UtroUp is a novel six zinc finger artificial transcription factor that recognises 18 base pairs of t...