Document Detail

An optimal mounting frame to reduce flexural stresses of bioprosthetic heart valves.
MedLine Citation:
PMID:  8003759     Owner:  NLM     Status:  MEDLINE    
Recent studies suggest that sharp bending of valve leaflets during the opening phase may be the reason for much of the mechanical failure of bovine pericardial bioprostheses. Sharp bending of the valve leaflets is promoted by the rigid, non expanding stents upon which the leaflets are mounted. We hypothesized that sharp bends and the associated flexural stresses could be significantly reduced by incorporating a stent that expands with the recipient aorta during systolic valve opening. We therefore modeled the opening and closing sequence of a trileaflet bovine pericardial valve with such an expanding supporting stent using our own finite element analysis software. Six different degrees of expansion were simulated, ranging from 2% to 25% expansion measured at the level of the stent post tips. Our results show that a 15% expansion is optimal, for the analyzed valve, because it eliminates the compressive flexural stresses at the commissures. Expansions below 15% were not sufficient to reduce flexural stresses, whereas expansions greater than 20% induced excessive tension in the valve cusps.
I Vesely; S Krucinski; M A Dokainish; G Campbell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  40     ISSN:  1058-2916     ISO Abbreviation:  ASAIO J.     Publication Date:    1994 Apr-Jun
Date Detail:
Created Date:  1994-07-18     Completed Date:  1994-07-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-205     Citation Subset:  IM    
Department of Electrical Engineering, University of Western Ontario, London, Canada.
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MeSH Terms
Heart Valve Prosthesis*
Models, Cardiovascular*
Nonlinear Dynamics
Prosthesis Design
Prosthesis Failure
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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