Document Detail

An open trial on short-term omeprazole therapy for gastric and duodenal ulcers.
MedLine Citation:
PMID:  1884955     Owner:  NLM     Status:  MEDLINE    
Omeprazole, a proton pump inhibitor, is a potent and long-acting gastric acid reducing agent. To assess its short-term efficacy and safety, 27 gastric ulcers (GU) and 40 duodenal ulcers (DU) in 64 patients were treated with 20 mg. Omeprazole was given once daily. At 2 weeks, the healing rate for gastric ulcers was 66% (18/27) and for duodenal ulcers, 78% (31/40). At 4 weeks, the healing rate was 85% and 95% for GU and DU, respectively. Pain relief was achieved after 2 weeks in 62% with GU and 61% in DU. There were no significant side effects noted during the treatment course. Omeprazole is effective and safe in the treatment of gastric and duodenal ulcers.
J D Sollano; A C Espiritu; S Z Alvarez; J Y Perez
Related Documents :
7976095 - Vein surgery with or without skin grafting versus conservative treatment for leg ulcers...
3130125 - Highly selective vagotomy and duodenal ulcers that fail to respond to h2 receptor antag...
3244995 - Surgery is preferable in patients with severe chronic peptic ulcer disease.
20430295 - Endovenous laser therapy in the treatment of lower-limb venous ulcers.
22325725 - Scanning electron microscopy and roughness study of dental composite degradation.
20562795 - Green light laser (ktp, 80 w) for the treatment of benign prostatic hyperplasia.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Gastroenterologia Japonica     Volume:  26 Suppl 3     ISSN:  0435-1339     ISO Abbreviation:  Gastroenterol. Jpn.     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-10-04     Completed Date:  1991-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0152744     Medline TA:  Gastroenterol Jpn     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  271-4     Citation Subset:  IM    
University of Santo Tomas, Manila, Philippines.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Drug Evaluation
Duodenal Ulcer / drug therapy*
Middle Aged
Omeprazole / therapeutic use*
Stomach Ulcer / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Variceal bleeding after endoscopic injection sclerotherapy: an analysis of 108 subjects undergoing e...
Next Document:  Diagnostic approaches and treatment of peptic ulcer at Chulalongkorn University Hospital, Bangkok.