Document Detail

The onset of neuromuscular block at the masseter muscle as a predictor of optimal intubating conditions with rocuronium.
MedLine Citation:
PMID:  10434167     Owner:  NLM     Status:  MEDLINE    
After an intubating dose of rocuronium satisfactory intubating conditions are achieved before the onset time at the adductor pollicis. We examined the possibility that measurement of the relaxation of the masseter muscle is a more appropriate guide when determining the intubating time. Simultaneous accelerometry with a 0.1-Hz single twitch stimulation of the chin and thumb was performed in 20 patients after 0.6 mg kg-1 rocuronium. We observed a significantly more brief mean lag time and onset time at the masseter muscle (22.5 and 61 vs. 32.5 and 160 s). The corresponding mean relaxation at the onset time was also significantly more pronounced at the masseter muscle (99.6 vs. 97.6%). A mean onset time at the masseter muscle of 61 s as produced by rocuronium corresponds clinically with excellent or good intubating conditions. From these results, we suggest that measurement of the onset time of muscle relaxation at the masseter muscle appears to be a better predictor of good intubating conditions than measurements made using the adductor pollicis muscle after administration of rocuronium.
J C De Mey; L De Baerdemaeker; M De Laat; G Rolly
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  16     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-09-17     Completed Date:  1999-09-17     Revised Date:  2004-11-18    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  387-9     Citation Subset:  IM    
Department of Anaesthesia, University Hospital, Gent, Belgium.
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MeSH Terms
Intubation, Intratracheal*
Masseter Muscle / drug effects*
Middle Aged
Muscle Relaxation / drug effects
Neuromuscular Blockade*
Neuromuscular Nondepolarizing Agents*
Time Factors
Reg. No./Substance:
0/Androstanols; 0/Neuromuscular Nondepolarizing Agents; 143558-00-3/rocuronium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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