Document Detail

The onset of amyotrophic lateral sclerosis.
MedLine Citation:
PMID:  16484651     Owner:  NLM     Status:  MEDLINE    
Two patients in whom both the neurological examination and electromyography (EMG) were normal prior to the onset of amyotrophic lateral sclerosis (ALS) are reported. In each patient, the onset of ALS some 18 months later was clearly defined clinically and confirmed by subsequent EMG studies. These unique observations show that ALS commences at a defined time, and that there is early generalisation with an initial phase of rapid progression.
M de Carvalho; M Swash
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  77     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-17     Completed Date:  2006-03-24     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  388-9     Citation Subset:  IM    
Department of Neurology, Hospital de Santa Maria, Av. Prof. Egas Moniz, 1649 Lisbon, Portugal.
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MeSH Terms
Disease Progression
Follow-Up Studies
Middle Aged
Motor Neuron Disease / diagnosis*
Neurologic Examination*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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