| An ongoing pregnancy from two waves of follicles developing during a long follicular phase of the same cycle. | |
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MedLine Citation:
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PMID: 20138269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To report an ongoing pregnancy after in vitro fertilization (IVF) with ovarian stimulation using a gonadotropin-releasing hormone (GnRH) antagonist that resulted in two waves of follicular growth. DESIGN: Case report. SETTING: University of Toronto affiliated infertility clinic. PATIENT(S): A 33-year-old woman with a 3-year history of secondary infertility. INTERVENTION(S): In vitro fertilization and embryo transfer. MAIN OUTCOME MEASURE(S): Ongoing pregnancy. RESULT(S): This patient successfully conceived after the GnRH antagonist-induced demise of the first cohort of follicles and the emergence of a second wave of follicles followed by oocyte retrieval on cycle day 30 and fresh embryo transfer. CONCLUSION(S): This case report is consistent with previous observations of multiple waves of follicle recruitment and growth per cycle. The window of implantation may not be adversely affected by prolonged or even variable estrogen exposure in the follicular phase of the cycle. |
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Authors:
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Yaakov Bentov; Navid Esfandiari; Asli Gokturk; Eliezer Burstein; Ofer Fainaru; Robert F Casper |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 94 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-25 Completed Date: 2010-06-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 350.e8-11 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Toronto Centre for Advanced Reproductive Technology, Toronto, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Embryo Transfer* / methods Female Fertilization in Vitro / methods Follicular Phase / drug effects, physiology* Gonadotropin-Releasing Hormone / antagonists & inhibitors Hormone Antagonists / pharmacology Humans Ovarian Follicle / drug effects, growth & development* Ovulation / drug effects, physiology* Ovulation Induction* / methods Pregnancy Pregnancy Outcome |
| Chemical | |
Reg. No./Substance:
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0/Hormone Antagonists; 33515-09-2/Gonadotropin-Releasing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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