| A one-year survey of candidemia in Belgium in 2002. | |
MedLine Citation:
|
PMID: 15635977 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A total of 211 episodes of bloodstream yeast infections in 207 patients, hospitalized in 28 Belgian hospitals participating in a National Surveillance Program, were evaluated. A total of 81% of the patients were more than 50 years of age. Candida albicans was the cause of infections in 55% of patients, 22% were due to C. glabrata and 13% to C. parapsilosis. The most common predisposing factors were antibacterial therapy (42%), residence in an intensive care unit (32.9%) and presence of an intravascular catheter (29.7%). Most patients had more than one predisposing factor. Fluconazole alone or in association with another antifungal agent was the treatment of choice for 89.7% of the cases. In vitro susceptibility testing of the isolates revealed that 99% were susceptible to amphotericin B, 95% to 5-fluorocytosine, 82% to fluconazole and 69% to itraconazole. Resistance to azoles was more common among C. glabrata isolates in the elderly. We conclude that the frequency of C. albicans infection is decreasing in Belgium and this is associated with the emergence of other species, most notably, C. glabrata. |
Authors:
|
D Swinne; M Watelle; C Suetens; K Mertens; P A Fonteyne; N Nolard |
Related Documents
:
|
320297 - Scarlet fever and group a streptococcal surgical wound infection traced to an anal carr... 3610437 - Systemic candidiasis in heroin abusers. cutaneous findings. 15688097 - Treatment of onychomycosis: pros and cons of antifungal agents. 8580277 - Prospective study of fluconazole suspension for the treatment of oesophageal candidiasi... 10966257 - Correlation between endotoxin level and bacterial count in bronchoalveolar lavage fluid... 9849767 - Substance use and abuse among patients with comorbid dysthymia and substance disorder. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Epidemiology and infection Volume: 132 ISSN: 0950-2688 ISO Abbreviation: Epidemiol. Infect. Publication Date: 2004 Dec |
Date Detail:
|
Created Date: 2005-01-07 Completed Date: 2005-01-26 Revised Date: 2010-05-17 |
Medline Journal Info:
|
Nlm Unique ID: 8703737 Medline TA: Epidemiol Infect Country: England |
Other Details:
|
Languages: eng Pagination: 1175-80 Citation Subset: IM |
Affiliation:
|
Mycology Section, Scientific Institute of Public Health, Brussels, Belgium. d.swinne@iph.fgov.be |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Antifungal Agents / therapeutic use Belgium / epidemiology Candida albicans / drug effects, pathogenicity Candida glabrata / drug effects, pathogenicity Candidiasis / drug therapy, epidemiology*, therapy Drug Resistance, Fungal Female Fungemia / drug therapy, epidemiology*, therapy Hospitalization / statistics & numerical data Humans Incidence Male Middle Aged Population Surveillance* |
| Chemical | |
Reg. No./Substance:
|
0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Influenza and pneumonia hospitalizations in Ontario: a time-series analysis.
Next Document: Prevalence of Escherichia coli and Salmonella spp. in street-vended food of open markets (tianguis) ...