Document Detail


A one-dimensional transient model of electrical field flow fractionation.
MedLine Citation:
PMID:  15624184     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A well-developed classical theory is available for constant-voltage electrical field flow fractionation (EFFF). Recent experimental research, however, has demonstrated that pulsed fields may enhance retention in some cases. A generalized mathematical approach is presented for the prediction of retention ratios for any field type, pulsed or constant. The methodology is applied and demonstrated for a square wave protocol. Complex concentration profiles arise wherein particles are focused either towards the walls or into the channel center. The computational results indicate that pulsation can either increase retention time or decrease retention time by manipulating the effective electric field and suggest that separation resolution may also be improved.
Authors:
Joseph J Biernacki; Naitik Vyas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Electrophoresis     Volume:  26     ISSN:  0173-0835     ISO Abbreviation:  Electrophoresis     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-10     Completed Date:  2005-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8204476     Medline TA:  Electrophoresis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  18-27     Citation Subset:  IM    
Affiliation:
Tennessee Technological University, Department of Chemical Engineering, Cookeville, TN 38501, USA. jbiernacki@tntech.edu
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MeSH Terms
Descriptor/Qualifier:
Electricity
Fractionation, Field Flow*
Models, Chemical*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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