| A one-center experience with pediatric percutaneous renal biopsy and histopathology in Ankara, Turkey. | |
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MedLine Citation:
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PMID: 18696251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study we evaluated the indications, complications, and the spectrum of histopathological results of percutaneous renal needle biopsy (PRNB) performed in our clinic. Between June 1990 and December 2006, 679 PRNBs were performed on native kidneys of 614 children (304 boys, 310 girls) with a mean age of 10.4 years. Most frequent indications for PRNB were nephrotic syndrome (47%), hematuria, and/or proteinuria (15.9%), acute renal failure (14.6%) and complex renal manifestations (18.9%). The overall complication rate was 15.2%. The most common complications were perirenal hematoma (12.4%) and macroscopic hematuria (2.6%). The most frequent histopathological group of diseases were glomerulopathies; these were diagnosed in 376 patients (61.2%) and included membranoproliferative glomerulonephritis (11.1%), mesangial proliferation (10.7%), diffuse proliferative glomerulonephritis (7.7%), and focal segmental glomerulosclerosis (7.3%) as the most frequent. The second most frequent group of histopathology was manifestations secondary to systemic diseases; these were shown in 195 patients (31.8%). Amyloidosis (11.4%) and Henoch-Schönlein nephritis (9.9%) made the majority of this group. In conclusion, our study demonstrated that PRNB is a safe procedure with usually transient complications showing the most frequent renal diseases that cause diagnostic and therapeutic difficulties for pediatric nephrologists. |
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Authors:
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Gülay Demircin; Ali Delibaş; Kenan Bek; Ozlem Erdoğan; Mehmet Bülbül; Sahika Baysun; Ayşegül Oksal; Leyla Memiş; Ayşe Oner |
Publication Detail:
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Type: Journal Article Date: 2008-08-12 |
Journal Detail:
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Title: International urology and nephrology Volume: 41 ISSN: 1573-2584 ISO Abbreviation: Int Urol Nephrol Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0262521 Medline TA: Int Urol Nephrol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 933-9 Citation Subset: IM |
Affiliation:
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Department of Pediatric Nephrology, Dr Sami Ulus Children's Hospital, Ankara, Turkey. gulaydemircin@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Biopsy, Needle / adverse effects, methods* Child Child, Preschool Female Hospitals, Pediatric Humans Immunohistochemistry Infant Infant, Newborn Kidney Diseases / diagnosis, pathology* Male Risk Assessment Risk Management Sensitivity and Specificity Severity of Illness Index Sex Factors Turkey Urban Population Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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