Document Detail

The oncologic safety and functional preservation of supraglottic partial laryngectomy.
MedLine Citation:
PMID:  20015754     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to evaluate the appropriateness of the conservative surgery as the initial treatment of supraglottic cancer by the comparative study of supraglottic partial laryngectomy with radiation therapy. METHODS: We analyzed 48 patients diagnosed as having supraglottic cancer who underwent supraglottic partial laryngectomy and 20 patients treated with radiation therapy as initial treatment from 1991 to 2005. Oncologic safety was evaluated by comparison of survival rates. Swallowing test was performed with videoesophagofluoroscopy under the category of the pharyngeal phase and the presence or absence of aspiration. Phonologic analysis was performed with acoustic waveform analysis and stroboscopy. RESULTS: Positive resection margin was observed in 12 of the patients who received supraglottic partial laryngectomy (SPL), and its relationship with the primary subsite was evaluated. For the patients in stages I and II, the overall survival rate in each of the SPL group and the radiotherapy (RTx) group was 87% and 80%, respectively. For the patients in stages III and IV, the overall survival rate was 87% and 80%, respectively. On evaluation of swallowing and phonation function, no significant difference was noted between the SPL group and the RTx group. CONCLUSION: This study suggests that for patients with supraglottic cancer, SPL provides acceptable survival, swallowing, and phonologic results in comparison with radiation therapy.
Je Young Chun; Young Ho Kim; Eun Chang Choi; Hyung Kwon Byeon; Jinsei Jung; Se-Heon Kim
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-06-10
Journal Detail:
Title:  American journal of otolaryngology     Volume:  31     ISSN:  1532-818X     ISO Abbreviation:  Am J Otolaryngol     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000029     Medline TA:  Am J Otolaryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea.
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MeSH Terms
Deglutition / physiology*
Follow-Up Studies
Glottis / physiopathology
Laryngeal Neoplasms / physiopathology,  radiotherapy,  surgery*
Laryngectomy / methods*
Middle Aged
Recovery of Function / physiology*
Retrospective Studies
Treatment Outcome
Video Recording
Voice Quality / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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