Document Detail

An onchocercal nodule appearing during diethylcarbamazine therapy.
MedLine Citation:
PMID:  7149099     Owner:  NLM     Status:  MEDLINE    
We describe the appearance of an onchocercal nodule in a patient during treatment with diethylcarbamazine (DEC). This is a unique occurrence. DEC has been employed in the treatment of onchocerciasis for many years, but there have been no reports of any effects of DEC on nodules. Histopathological studies in which nodules have been examined before and after treatment of patients with DEC have not revealed any changes induced by such treatment. The histological appearance of this nodule is described, and the probable mechanism of its enlargement is discussed.
E S Boye; D H Connor
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  31     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  1982 Nov 
Date Detail:
Created Date:  1983-01-19     Completed Date:  1983-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1123-7     Citation Subset:  AIM; IM    
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MeSH Terms
Dermatitis / parasitology,  pathology
Diethylcarbamazine / therapeutic use*
Microfilaria / drug effects,  parasitology
Onchocerciasis / drug therapy*,  parasitology,  pathology
Reg. No./Substance:

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