Document Detail

The once and future state of percutaneous mitral valve repair.
MedLine Citation:
PMID:  23013128     Owner:  NLM     Status:  In-Data-Review    
There has been a great deal of interest in percutaneous mitral valve repair techniques in recent years, with several devices undergoing animal testing and clinical trials. Percutaneous annuloplasty and leaflet repair devices are currently in development, and while safety rates have generally been equal or superior to conventional surgical techniques, efficacy has been suboptimal. Most current percutaneous mitral valve repair devices can only reduce regurgitant volumes by approximately 20-40%, but these reductions may be enough to treat high-risk patients, including the elderly and those with comorbidities, who are otherwise ineligible for surgery. An analysis of how these devices alter the geometry and mechanics of the mitral valve apparatus can provide insight into long-term efficacy and durability and may lead to improvements in the reduction of mitral regurgitation. In the future, multiple percutaneous techniques may be utilized in combination to increase overall efficacy. In this article, we report on percutaneous mitral valve repair techniques with published clinical or animal data.
Steven M Boronyak; W David Merryman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future cardiology     Volume:  8     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  779-93     Citation Subset:  IM    
Department of Biomedical Engineering, Vanderbilt University Nashville, Room 9445D MRB IV-Langford, 2213 Garland Avenue, Nashville, TN 37232-0493, USA.
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