Document Detail


The old-age heart: normal aging changes which can produce or mimic cardiac disease.
MedLine Citation:
PMID:  3048829     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The elderly segment of our society may triple by the year 2050. Specific cardiovascular data on the normal aging heart will be needed to provide proper medical and surgical therapy for this patient group. This report reviews normal aging changes of the very elderly heart. Expected or normal aging changes include brown atrophy of the myocardium, increased subepicardial fat, focal amyloid deposits, sigmoid-shaped ventricular septum, and calcific deposits in the aortic valve, mitral annulus and epicardial coronary arteries. Certain normal aging changes may produce clinical heart disease: aortic valve calcium (aortic stenosis), mitral valve annular calcium (mitral stenosis), amyloid deposits (amyloid heart disease). Certain normal aging changes may mimic heart disease: sigmoid-shaped ventricular septum (hypertrophic cardiomyopathy), mitral leaflet "buckling" (floppy mitral valve).
Authors:
B F Waller
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  11     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-10-31     Completed Date:  1988-10-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  513-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, Indiana University School of Medicine, Indianapolis.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over*
Aging / physiology*
Heart / physiopathology*
Heart Diseases / diagnosis*,  etiology
Heart Valve Diseases / etiology
Humans
Myocardium / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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