Document Detail

Is old age a contraindication for surgical treatment in acute aortic dissection? A demographic study of national database registry in Taiwan.
MedLine Citation:
PMID:  18304127     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Acute aortic dissection is usually presented as a surgical emergent condition with high mortality rate. Whether any patient of an advanced age suffering from acute aortic type A dissection or complicated type B dissection should be referred for surgery still deserves debating. MATERIALS AND METHODS: A retrospective study including 5654 patients with acute aortic dissection was collected from the National Health Insurance Databases from 1996 to 2001. Age, initial treatment modality, and the late outcome were the main factors to be investigated. Patients are grouped into the young age group when ages are less or equal to 70 and the old age group when over 70. We further subdivided both groups into operative and nonoperative subgroups, respectively, depending on patients receiving surgical intervention for acute aortic dissection or not. The endpoint mortality was defined by the patient death either related to or unrelated to cardiac causes. RESULTS: A total of 5654 cases are with the mean age of 65.6 +/- 14.0 years. The percentage of patients receiving operation was inversely related to the patient's age significantly (p < 0.05). In the old age group, the operative subgroup had both significantly higher survival rate at six-year follow-up than the nonoperative group for both patients on admission and 30-day survivors (43.4 +/- 3.5% vs. 29.8 +/- 2.3%, p < 0.05; 70.0 +/- 4.5% vs. 36.0 +/- 2.8%, p < 0.05). The annual attrition rates of mortality were significantly higher in the nonoperative subgroup for both patients on admission and 30-day survivors (p < 0.05). CONCLUSION: The trend toward more conservative treatment in the elderly still occurs in our common practice even with improving surgical techniques. In our study, we suggest that pertinent surgical strategies for acute aortic dissection are necessary to improve the outcome in elderly patients.
I-Hui Wu; Hsi-Yu Yu; Chih-Ho Liu; Yih-Sharng Chen; Shoei-Shun Wang; Fang-Yue Lin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  23     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-02-28     Completed Date:  2008-05-08     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  133-9     Citation Subset:  IM    
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
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MeSH Terms
Acute Disease
Age Factors
Aged, 80 and over
Aneurysm, Dissecting / drug therapy,  mortality,  surgery*
Aortic Aneurysm, Thoracic / drug therapy,  mortality,  surgery*
Decision Making
Geriatric Assessment
Insurance, Health
Middle Aged
Postoperative Period
Retrospective Studies
Survival Analysis
Taiwan / epidemiology
Time Factors
Treatment Outcome
Comment In:
J Card Surg. 2009 Jan-Feb;24(1):99-100   [PMID:  18793236 ]

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