Document Detail

On- and off-responses in photopic electroretinogram in complete and incomplete types of congenital stationary night blindness.
MedLine Citation:
PMID:  3498069     Owner:  NLM     Status:  MEDLINE    
The on- and off-responses of photopic electroretinogram (ERG) were recorded by rectangular light stimuli in 13 patients with complete type and 9 patients with incomplete type of congenital stationary night blindness. The positive on-response (b-wave) was significantly smaller in both types than in normal subjects (P less than 0.001). The rapid off-response was normal in complete type patients, but was significantly smaller in incomplete type patients than in normal subjects (P less than 0.001). Since the rapid off-response mainly reflects the decay of the late receptor potential of the cones, incomplete type patients may have a visual disturbance in the cone itself. Normal rapid off-response with abnormal on-response in complete type patients suggests the existence of a photopic visual disturbance in the middle retinal layer. These results strongly suggest that these two types of congenital stationary night blindness have a different pathogenesis in the photopic visual pathway.
Y Miyake; K Yagasaki; M Horiguchi; Y Kawase
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese journal of ophthalmology     Volume:  31     ISSN:  0021-5155     ISO Abbreviation:  Jpn. J. Ophthalmol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-09-25     Completed Date:  1987-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0044652     Medline TA:  Jpn J Ophthalmol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  81-7     Citation Subset:  IM    
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MeSH Terms
Electroretinography / methods*
Middle Aged
Night Blindness / classification,  congenital*,  physiopathology
Reference Values

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