Document Detail

The odds of delivering one, two or three extremely low birth weight (< 1000 g) triplet infants: a study of 3288 sets.
MedLine Citation:
PMID:  12442597     Owner:  NLM     Status:  MEDLINE    
The odds of an individual triplet pregnancy to end with neonates weighing < 1000 g (extremely low birth weight [ELBW]) are unknown. We analyzed a nationwide perinatal database collected by Matria Healthcare, Inc. (Marietta, GA) to select from 3288 triplets those weighing 500-1000 g, delivered during the period 1988-2000 in the United States. We counted the number of sets with one, two, and three ELBW neonates and compared the incidence of ELBW infants between the subsets of nulliparas and multiparas. The odds of delivering at least one ELBW infant was significantly higher among nulliparas (1:8) than among multiparas (1:14), Odds Ratio (OR) 1.9, 95% Confidence Interval (CI) 1.9, 2.5. The odds of having at least two ELBW sibs in nulliparas (1:16) is twice higher than in multiparas (1:31), OR 2.0, 95% CI 1.3, 2.9. Nulliparas and multiparas had similar odds of delivering three ELBW infants (1:29 versus 1:40, OR 1.3, 95% CI 0.9, 2.1). Nulliparas are at significantly increased risk of delivering one or two ELBW triplets. This observation is no less than alarming and highlighted by the exceptionally high risk of major neurological deficits reported among ELBW infants.
Isaac Blickstein; Debbie L Jacques; Louis G Keith
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  30     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2002  
Date Detail:
Created Date:  2002-11-21     Completed Date:  2003-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  359-63     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel.
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MeSH Terms
Birth Weight
Gestational Age
Infant, Newborn
Infant, Very Low Birth Weight*
Israel / epidemiology
Pregnancy, Multiple / statistics & numerical data*
Triplets / statistics & numerical data*
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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