Document Detail


The ocular complications of mustard gas poisoning and their association with the respiratory system involvement: an experience in 112 Iranian veterans.
MedLine Citation:
PMID:  22053994     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective: To investigate ocular complications and their association with respiratory involvement in 112 patients with first exposure of mustard gas for at least 19 years ago.Design: Cross-sectional study. Participants: One hundred and twelve veterans (224 eyes) with documented exposure to sulphur mustard (SM) for the first time. Methods: All participants were interviewed and clinically examined by an ophthalmologist and a specialist in respiratory disease. Data filed from the exposure time and regular follow-ups thereafter were reviewed. The patients were categorized in three subgroups according to the severity of respiratory system involvement as determined by spirometry (normal, mild, and moderate-severe). Results: Subjective and objective ocular problems were documented in 83.9 and 70.6% of victims, respectively. Normal, mild, and moderate-severe respiratory system problems were present in 37.5, 22.3 and 40.2% of cases, respectively. Abnormal ocular findings were severe conjunctival vascular tortuosity (65.2%, mean: 13.71 years after exposure), corneal neovascularization (19.6%, mean: 16.54 years after exposure), conjunctival/limbal vessels with ampulliform dilatation (17.9%, mean: 9.33 years after exposure), and delayed keratitis (9.8%, mean: 19.54 years after exposure). The ocular abnormal findings were significantly more frequent in victims with moderate-severe respiratory system involvement. Conclusion: Structural ocular abnormalities are frequently found in patients with long-term history of mustard gas intoxication. These abnormalities are more common in severe respiratory system involvement.
Authors:
Mohammad Reza Sedghipour; Abdollah Shenasi; Mohammad Bagher Rahbani Nobar; Rohollah F Foulad; Ramin Amini
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-7
Journal Detail:
Title:  Cutaneous and ocular toxicology     Volume:  -     ISSN:  1556-9535     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101266892     Medline TA:  Cutan Ocul Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Tabriz University of Medical Sciences , Tabriz , Iran.
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