Document Detail

The occurrence of HR1b in the venom of the snake Okinawa habu (Protobothrops flavoviridis).
MedLine Citation:
PMID:  18256489     Owner:  NLM     Status:  MEDLINE    
This study describes the first isolation of hemorrhagic metalloproteinase HR1b from the venom of Okinawa habu, and its cDNA cloning. The substrate specificity of isolated HR1b definitely differed from that of HR1a, further supporting the presence of a metalloproteinase distinguishable from HR1a in the venom of Okinawa habu. The deduced amino acid sequence of HR1b showed 99.67% identity with HR1b of Amami habu, with only two amino acid residue replacements.
Nobuya Morine; Seiko Matsuda; Koki Terada; Hironori Iwasaki; Hirosuke Oku
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Publication Detail:
Type:  Journal Article     Date:  2008-02-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  72     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-25     Completed Date:  2008-08-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  591-4     Citation Subset:  IM    
United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.
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MeSH Terms
Amino Acid Sequence
Base Sequence
Chromatography, High Pressure Liquid
Crotalid Venoms / enzymology*
DNA Primers
Electrophoresis, Polyacrylamide Gel
Metalloproteases / chemistry,  isolation & purification*,  metabolism
Molecular Sequence Data
Reg. No./Substance:
0/Crotalid Venoms; 0/DNA Primers; EC 3.4.-/Metalloproteases

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