Document Detail

The obstetrical management of patients with immunologic thrombocytopenic purpura.
MedLine Citation:
PMID:  6126403     Owner:  NLM     Status:  MEDLINE    
Pregnant women with immunologic thrombocytopenic purpura (ITP) run the risk of complications during pregnancy and labor, mainly due to the possibility of hemorrhage. Antibodies pass through the placenta, causing a transient, but dangerous thrombocytopenia in the fetus and infant. Four women with ITP, having five deliveries, are presented, showing that the modern treatment of these patients includes corticosteroids during pregnancy, thrombocyte transfusion during labor, and splenectomy being or after the pregnancy in selected cases. Cesarean section is not indicated for the disease per se, and fetal scalp blood sampling for thrombocyte count during labor is not necessary. The newborn needs immediate, careful control and, if necessary, thrombocyte transfusion and even steroids. Prolonged follow-up of the infants is necessary.
I Kessler; M Lancet; R Borenstein; A Berrebi; B M Mogilner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  20     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1982 Feb 
Date Detail:
Created Date:  1982-12-02     Completed Date:  1982-12-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  23-8     Citation Subset:  IM    
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MeSH Terms
Blood Transfusion
Delivery, Obstetric
Infant, Newborn
Platelet Count
Prednisone / therapeutic use
Pregnancy Complications, Hematologic / therapy*
Purpura, Thrombocytopenic / therapy*
Reg. No./Substance:

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