Document Detail


The obstetric management of sickle cell disease.
MedLine Citation:
PMID:  22113135     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Sickle cell disease (SCD) is the most common inherited disease worldwide and is associated with anaemia and intermittent severe pain. Pregnant women who are affected have increased maternal and fetal mortality and morbidity. In view of this obstetricians should have an awareness of this condition and its complications, and pregnancies in women with SCD should be managed by a multidisciplinary team with experience of high risk pregnancies. Ideally women should be seen preconceptually for optimisation of their SCD and partner screening. Antenatal care should include regular outpatient visits with regular monitoring for pre-eclampsia and of fetal growth. Blood transfusion should be used for the treatment of acute anaemia, acute chest syndrome or acute stroke but there is not sufficient evidence currently to recommend its use prophylactically. There is an increased prevalence of sickle crisis during pregnancy and patients should be monitored carefully throughout this time.
Authors:
Jo Howard; Eugene Oteng-Ntim
Related Documents :
18696075 - Basic clinical examination skills may save lives.
17187835 - Goats may experience reproductive failures and shed coxiella burnetii at two successive...
8781705 - Intravenous immunoglobulin replacement therapy for common variable immunodeficiency dur...
1294525 - Treatment of bacteriuria in pregnancy with single dose fosfomycin trometamol: a review.
25397445 - The use of tdm in pregnant hiv-positive women: a retrospective cross-sectional review o...
4056295 - Ectoparasitic infestation of the lashes.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-21
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  -     ISSN:  1532-1932     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The presence of high level soluble herpes virus entry mediator in sera of gastric cancer patients.
Next Document:  Predictive genetic testing and beyond: a theory of engagement.